Endocrine Abstracts

Spermatogenesis is a complex process that requires the formation of junctional complexes between somatic Sertoli cells and germ cells and hormonal regulation of the Sertoli cells. Androgens and oestrogens are both synthesised in the testis. In adults Sertoli cells contain both androgen receptor (AR) and oestrogen receptor beta (ERß). In the present study we used a transformed Sc cell line (SK11) that was prepared from the testes of mice expressing the large T antigen. Whe...